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CATEGORIES:Academics,Natural & Applied Sciences Division,Biology
DESCRIPTION:Title: "A Life in Lipids: Reflections on my Metabolic Journey. 
 On Curiosity\, Collaboration\, and Double Bonds"\n\nAbstract: Most biomolec
 ules are polymers assembled from defined monomers—nucleotides\, amino acids
 \, or monosaccharides. Lipids\, however\, are distinct: rather than being b
 uilt from a single monomeric unit\, they are classified by a shared physica
 l property\, hydrophobicity. This fundamental difference presents unique ch
 allenges for cells\, particularly in how they sense environmental condition
 s\, regulate lipid biosynthesis\, and acquire lipids from their surrounding
 s. Using the eukaryotic baker’s yeast\, research in the McDonough lab focus
 es on understanding the regulation of lipid metabolism\, using unsaturated 
 fatty acid metabolism as a model system. We have found that there is cross-
 talk between the different classes of lipids affecting fatty acid metabolis
 m\, and yet\, highly specific response to different species of fatty acids.
  This talk will explore emerging principles of lipid sensing and regulation
 \, and how cells balance global lipid control with molecular specificity.\n
 \nBio: Dr. McDonough is a molecular biologist whose research focuses on the
  regulation of lipid metabolism. Now in her 31st and final year at Hope Col
 lege\, she reflects on a career dedicated to undergraduate education\, ment
 orship\, and lipid biology. Over her career\, she has guided dozens of unde
 rgraduates through independent research projects and into graduate\, profes
 sional\, and scientific careers\, and taught genetics and molecular biology
  across all levels of the curriculum. Her work in lipid biology began durin
 g her graduate training at Rutgers University with Dr. Chuck Martin\, where
  she studied the molecular biology of unsaturated fatty acid metabolism. Sh
 e continued this focus as a postdoctoral fellow with Dr. George Carman\, in
 vestigating the biochemistry of phospholipid metabolism. Dr. McDonough’s gr
 eatest success has been her long-standing partnership with Dr. Joseph Stuke
 y—sharing a life centered on talking science\, publishing together\, creati
 ng a home\, and raising their two sons.
DTEND:20260227T210000Z
DTSTAMP:20260412T054511Z
DTSTART:20260227T200000Z
GEO:42.786861;-86.104963
LOCATION:A. Paul Schaap Science Center\, 1019
SEQUENCE:0
SUMMARY:Biology Seminar Series - Dr. Ginny McDonough\, Hope College
UID:tag:localist.com\,2008:EventInstance_51497241503920
URL:https://calendar.hope.edu/event/biology-seminar-series-dr-ginny-mcdonou
 gh-hope-college
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