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35 East 12th Street, Holland, MI 49423-3605
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SEMINAR SPEAKER: Dr. Tim Stowe, Cavalry Biosciences
TITLE: Engineering Growth Factors for Targeted Therapeutics
ABSTRACT: Growth factors are powerful secreted signaling proteins that play an important role in development, aging, and disease. While growth factors have broad therapeutic potential, their development is limited by widespread expression of cognate receptors and lack of tissue selectivity. Cavalry Biosciences uses protein engineering to build tissue selective growth factors with pharmacology selectively tuned for specific indications. The platform has given rise to programs in Orphan Growth Disorders, Dry Eye Disease associated with Meibomian Gland Dysfunction (MGD), Muscular Dystrophies, and Atherosclerosis. Cavalry is planning to progress the Dry Eye and Growth Disorder programs into clinical development in 2024.
BIO: Tim currently serves as Senior Vice President of research at Cavalry Biosciences, a San Francisco-based drug discovery startup he co-founded in 2021. Tim graduated from Hope College with a BS in Biology in 2003 and went on to earn his PhD in Cancer Biology from Stanford University in 2011, where he studied the role of the microtubule cytoskeleton and primary cilium in cell signaling. After a brief postdoc at UCSF working on neurodevelopment and epilepsy, Tim transitioned to the biotechnology industry. Over the past 10 years, he has been working at startups in the Bay Area including Silver Creek Pharmaceuticals, Unity Biotechnology, and Encoded Therapeutics. He lives in South San Francisco with his wife and daughter.
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