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VERSION:2.0
CALSCALE:GREGORIAN
PRODID:iCalendar-Ruby
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CATEGORIES:Academics,Natural & Applied Sciences Division,Chemistry and Bioc
 hemistry
DESCRIPTION:SEMINAR SPEAKER: Dr. Markita Landry\, UC Berkeley\n\nTITLE: “Ch
 anges in neurochemical signaling that affect social behavior in animals”\n\
 nABSTRACT: Neurons communicate through neurochemical signals that either ac
 t across synapses via wired transmission or diffuse beyond the synaptic cle
 ft to influence broader neural circuits through volume transmission. Neurom
 odulators such as dopamine\, serotonin\, and the neuropeptide oxytocin fall
  into this latter category and have long been central targets of psychiatri
 c therapeutics\, yet their spatial and temporal dynamics were previously in
 accessible to direct imaging. We present a library of nanoscale near-infrar
 ed fluorescent nanosensors that enable synaptic-scale imaging of dopamine\,
  serotonin\, and oxytocin signaling in living brain tissue. Using these too
 ls\, we show that oxytocin nanosensors can directly visualize neuromodulato
 r dynamics underlying non-reproductive peer social interactions and reveal 
 impaired oxytocin signaling in animals with reduced social preference. Toge
 ther\, this work establishes a new framework for studying the neurochemical
  basis of social behavior and its dysregulation in neuropsychiatric conditi
 ons such as autism spectrum disorder.\n\nBIO: Markita Landry is an associat
 e professor in the departments of Chemical and Biomolecular Engineering and
  Neuroscience at the University of California\, Berkeley. She received a B.
 S. in Chemistry and a B.A. in Physics from the University of North Carolina
  at Chapel Hill\, and a Ph.D. in Chemical Physics and a Certificate in Busi
 ness Administration from the University of Illinois at Urbana-Champaign\, f
 ollowed by an NSF postdoctoral fellowship at the Massachusetts Institute of
  Technology.\n\nHer research centers on imaging neuromodulation in the brai
 n\, studying lipid nanoparticle–cell membrane interactions\, and developing
  methods for genetic delivery in plants. She serves on scientific advisory 
 boards for major agricultural companies and is co-founder and CSO of Biophi
 lia Genetics. She has received over 40 career awards\, including honors fro
 m the Burroughs Wellcome Fund\, Schmidt Foundation\, McKnight Foundation\, 
 DARPA\, Beckman Foundation\, NSF\, and Sloan Foundation\, as well as the Vi
 lcek\, Blavatnik\, and Guggenheim prizes.
DTEND:20260220T220000Z
DTSTAMP:20260412T053137Z
DTSTART:20260220T210000Z
GEO:42.786861;-86.104963
LOCATION:A. Paul Schaap Science Center\, Auditorium 1000
SEQUENCE:0
SUMMARY:Chemistry + Biochemistry Necker's Technical Lecture
UID:tag:localist.com\,2008:EventInstance_50884029971566
URL:https://calendar.hope.edu/event/neckers-technical-lecture-3000
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